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The Brain Repair Group

The Brain Repair Group is based at Cardiff University in the UK. Our team are conducting pre-clinical research on neurodegenerative diseases, with a focus on Huntington's and Parkinson's disease. We have a wide range of projects underway, but a key aim is to develop a stem cell-derived cell therapy for Huntington's disease. 

Latest Publications

Epigenetic memory of Lateral Ganglionic Eminence derived hiPSCs cannot overcome barriers in authentic MSN differentiation

This paper investigates whether human iPSCs (hiPSC) derived from the lateral ganglionic eminence (LGE) retain sufficient epigenetic features of their original tissue to enhance their capacity to differentiate into striatal medium spiny neurons (MSN) compared to isogenic controls. 

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