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Techniques

At the Brain Repair Group, we use many techniques to research neurodegenerative diseases.

Molecular techniques

  • Single-cell sequencing

  • Single nuclei sequencing 

  • Bulk RNA sequencing

  • PCR

  • qPCR

  • DNA methylation

  • Generation of DNA plasmids

  • In-situ hybridization

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Anatomical studies

  • Immunohistology- bright field, floursence, golgi cox, crystal violet and HEMA

  • Microscopy- confocal, stereology

  • Tracing studies

  • ELISA assay

  • Analysis of human brain bank tissue

Cell culture

  • Primary cultures

  • Stem cell differentiation

  • Creation and validation of GMOs

  • Optogenetics

  • DREADD cell lines

  • Immunocytochemistry

  • Immunofluorescence

  • Bioengineering

  • CRISPR

  • Novel drug testing

  • Viral work

  • Multi electrode assays

Clinical trials

  • Partner labs for the TRIDENT and TRANSEURO clinical trials

  • Running of a clean room for 10 years

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